http://chem.skku.ac.kr/~cmyu/images/person3.gifEmail Address: Mcmyu@chem.skku.ac.kr
Home Page: [http]http://chem.skku.ac.kr/~cmyu
Telephone: +82-31-290-7067 / FAX: +82-31-290-7075

He is currently Professor of Chemistry at the Department of Chemistry of Sungkyunkwan University. He began his research as a graduate student at University of California where he involved in the enantioselective total synthesis of (+)-Ikarugamycin through Claisen protocol under the direction of Professor Mark J. Kurth during the periods of 1983 to 1987. From 1987 to 1989, he worked as Postdoctoral Fellow in the Laboratory of Professor E. J. Corey at Harvard University where he participated in the development of new chiral ligand for asymmetric synthesis. Before he joined the faculty of Sungkyunkwan University in 1993, he was a senior research scientist at the Korea Research Institute of Chemical Technology. He received Research Award from the Institute for Basic Science (2001). He is an Investigator of Center for Molecular Design and Synthesis ([http]CMDS) at the Korea Advanced Institute of Science and Technology since 1999 and also Investigator of Lab for Transition Metal Catalyzed Reactions established in 2001 by a grant from the Ministry of Science and Technology throughout a National Research Laboratory ([http]NRL) program.

Research Interests


Chan-Mo Yu's research interests involve the design of catalytic asymmetric synthesis in forming useful chiral substances. His research group developed synthetic routes to a variety of chiral alcohols through catalytic asymmetric allylic transfer reactions using new catalytic system and synergistic reagent. As an outgrowth of mechanistic speculation, the first observations of the dramatic acceleration of the allylic transfer reactions of aldehydes by the incorporation of the sulfur containing borane, silane, and alane with BINOL-Ti(IV) complex were made and extended to the development of new allylic transfer reactions in the production of chiral alcohols. As an extension for new reactions of synthetic utility that have been developed include the stereoselective synthesis of tetrahydropyrans from bifunctional sequential allylic transfer reactions with new BINOL-Ti(IV) complex.

And also, his laboratory carried out several research projects including new diastereoselective and enantioselective synthetic methods utilizing activated dihydropyran system using chiral Lewis acids.

Selected Publications


  1. Yu, C.-M.; Choi, H.-S.; Jung, W.-H.; Kim, H.-J.; Shin, J."Bifunctional Molecular Accelerator for Catalytic Asymmetric Allylation: R2MSR' (M=B,Al) as a Useful Synergetic Reagent" J. Chem. Soc., Chem. Commun. 1997, 761. [http]Full Article PDF
  2. Yu, C.-M.; Yoon, S.-K.; Choi, H.-S.; Baek, K. "Catalytic Asymmetric Pro-2-ynylation Involving the Use of the Bifunctional Synergetic Reagent Et2BSPri" J. Chem. Soc., Chem. Commun. 1997, 763. [http]Full Article PDF
  3. Yu, C.-M.; Yoon, S.-K.; Baek, K.; Lee, J.-Y. "Catalytic Asymmetric Allenylation: Regulation of the Equilibrium between Propargyl- and Allenylstannane during the Catalytic Process" Angew. Chem. 1998, 110, 2504; wwwAngew. Chem. Int. Ed. 37, 2392 . [http]Full Article PDF
  4. Yu, C.-M.; Yoon, S.-K.; Lee, S.-J.; Lee, J.-Y.; Kim, S. S. "Catalytic Asymmetric Allylic Transfer Reaction: (4-Trimethylsilylbut-2-ynyl)stannane as a New Reagent leading to the Enantioselective Synthesis of Dienyl Alcohols" J. Chem. Soc., Chem. Commun. 1998, 2749. [http]Full Article PDF
  5. Yu, C.-M.; Lee, S.-J.; Jeon, M. "Catalytic Asymmetric Dienylation of Achiral Aldehydes Using Buta-2,3-dienylstannane in the Presence of Chiral Lewis Acid and Synergetic Reagent" J. Chem. Soc. Perkin Trans. 1 1999, 3557.
  6. Yu, C.-M.; Lee, J.-Y.; Chun, K.; Lee, J.; Lee, Y. “Regulation of Diastereoselectivity through the Epimerisation of a Cyclic Intermediate in the Reaction of Cyclic Ketene Ortho Ester with Aldehydes” J. Chem. Soc. Perkin Trans. 1 2000, 3622.
  7. Yu, C.-M.; Jeon, M.; Lee, J.-Y.; Jeon, J. “Catalytic Asymmetric Allylic Transfer Reactions for the Enantioselective Synthesis of Dienyl and Enynyl Alcohols” Eur. J. Org. Chem. 2001, 4, 1143. [http]Full Article PDF
  8. Yu, C.-M.; Lee, J.-Y.; Chun, K.; Choi, I. “Asymmetric Routes in the Reaction of Cyclic Ketene Ortho Ester with Aldehydes Involving the Use of Chiral Lewis Acid” Chem. Commun. 2001, 2698. [http]Full Article PDF
  9. Yu, C.-M.; Lee, J.-Y.; So, B.-R.; Hong, J. “Sequential Catalytic Asymmetric Allylic Transfer Reaction: Enantioselective and Diastereoselective Construction of Tetrahydropyran Units” Angew. Chem. 2002, 114, 169; wwwAngew. Chem. Int. Ed. 41, 161 . [http]Full Article PDF

SKKU
440-746, 경기도 수원시 장안구 천천동 300 성균관대학교 자연과학캠퍼스 화학과 / TEL 031-290-7060 / FAX 031-290-7075
Department of Chemistry SungKyunKwan University Natural Science Campus Suwon 440-746 Korea
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