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Prof. Y. G. Kim 김양균

Email Address: ygkimmit@skku.edu
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Home Page: [http]http://chem.skku.ac.kr/~ygkim
Telephone: +82-31-299-4563/FAX: +82-31-290-4574

Vitae

  • 3/1985~2/1989 서울대학교 화학과, 이학사,
  • 3/1989~2/1991 서울대학교 화학과 생화학전공, 이학석사,
  • 9/1991~8/1995 Johns Hopkins University, Department of Environmental Health Sciences, Ph.D. 이학박사
  • 9/1995~1/2000 Massachusetts Institute of Technology, Department of Biology, Post-doctoral Associate
  • 2/2000~2/2002 Massachusetts Institute of Technology, Department of Biology, Research Scientist
  • 3/2002~2005 중앙대학교 의과대학 의학과, 조교수
  • 2006~현재 성균관대 화학과 부교수

Selected publications


  1. Kim, Y.-G. and Chandrasegaran, S. Chimeric restriction endonuclease. Proc. Natl. Acad. Sci. U.S.A. 91(3), 883-887, FEB 1 (1994)
  2. Kim, Y.-G., Cha, J. and Chandrasegaran, S. Hybrid restriction enzymes: Zinc finger fusions to FokI cleavage domain. Proc. Natl. Acad. Sci. U.S.A. 93(3), 1156-1160, FEB 6 (1996)
  3. Kim, Y.-G., Kim, P.S., Herbert, A. and Rich, A. Construction of a Z-DNA specific restriction endonuclease. Proc. Natl. Acad. Sci. U.S.A. 94(24), 12875-12879, NOV 25 (1997)
  4. Kim, Y.-G., Shi, Y., Berg, J.M. and Chandrasegaran, S. Site-specific cleavage of RNA-DNA hybrids by Zinc finger/FokI cleavage domain fusions. Gene 203(1), 43-49, DEC 5 (1997)
  5. Kim, Y.-G., Lowenhaupt, K., Schwartz, T. and Rich, A. The Interaction between Z-DNA and Zab domain of dsRNA Adenosine Deaminase Characterized Using Fusion Nucleases. J. Biol. Chem. 274, 19081-19086, JUL 2 (1999)
  6. Kim, Y.-G., Su, L., Maas, S., O'Neill, A. and Rich, A.

    Specific mutations in a viral RNA pseudoknot drastically change ribosomal frameshifting efficiency. Proc. Natl. Acad. Sci. U.S.A. 96(25), 14234-14239, DEC 7 (1999)

  7. Kim, Y.-G., Maas, S., Wang, S.C. and Rich, A. Mutational study reveals that tertiary interactions are conserved in ribosomal frameshifting pseudoknots of two luteoviruses. RNA 6, 1157-1165, August (2000)
  8. Kim, Y.-G.*, Lowenhaupt, K.*, Maas S., Herbert, A., Schwartz, T. and Rich, A. (*equal contribution) The Zab domain of the human RNA editing enzyme ADAR1 recognizes Z-DNA when surrounded by B-DNA. J. Biol. Chem. 275, 26828-26833, September 1 (2000)
  9. Bibikova, M, Carroll, D., Segal, D.J., Trautman, J.K., Smith, J., Kim, Y.-G. and Chadrasegaran, S. Stimulation of Homologous Recombination through Targeted Cleavage by Chimeric Nuclease. Mol. Cell. Biol. 21, 289-297, January (2001)
  10. Kim, Y.-G., Maas, S. and Rich, A. Comparative mutational analysis of cis-acting RNA signals for translational frameshifting in HIV-1 and HTLV-2. Nucleic Acids Res. 29, 1125-1131, March 1 (2001)
  11. Oh, D.B.*, Kim, Y.-G.* and Rich, A. (*equal contribution) Z-DNA binding proteins can act as potent effectors of gene expression in vivo. Proc. Natl. Acad. Sci. U.S.A. 99(26), 16666-16671, December 24 (2002)
  12. Kim, Y.-G.*, Muralinath*, M., Brandt, T., Pearcy, M., Hauns, K., Lowenhaupt, K., Jacobs, B.L. and Rich, A. (*equal contribution) A role for Z-DNA binding in vaccinia virus pathogenesis. Proc. Natl. Acad. Sci. U.S.A. 100(12), 6974-6979, June 10 (2003)
  13. Kim, Y.-G., Lowenhaupt, K., Oh, D.-B., Kim, K.K. and Rich, A. Evidence that vaccinia virulence factor E3L binds to Z-DNA in vivo: Implications for development of a therapy for poxvirus infection. Proc. Natl. Acad. Sci. U.S.A. 101(6), 1514-1518, Feb. 10 (2004)
  14. Choi, J.S., Kang, C.W., Jung, K., Yang, J.W., Kim, Y.-G. and Han, H. Synthesis of DNA triangles with vertexes of bis(terpyridine)iron(II) complexes. J. Am. Chem. Soc. 126(28), 8606-8607, July 21 (2004)
  15. Ha, S.C., Lokanath, N.K., Quyen, D.V., Wu, C.A., Lowenhaupt, K., Rich*, A., Kim, Y.-G.* and Kim, K.K.* (*corresponding authors) A poxvirus protein forms a complex with left-handed Z-DNA: Crystal structure of a Yatapoxvirus Zα bound to DNA. Proc. Natl. Acad. Sci. U.S.A. 101(40), 14367-14372, Oct. 5 (2004)
  16. Chi, Y.S., Jung, Y.H., Choi, I.S.* and Kim Y.-G.* (*corresponding authors) Surface-Initiated Growth of Poly d(A-T) by Taq DNA Polymerase. Langmuir 21(10), 4669-4673, May 10 (2005)
  17. Ha, S.C., Lowenhaupt, K., Rich, A., Kim Y.-G.* and Kim, K.K.* (*corresponding authors) Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases. Nature 437(7062), 1183-1186, October 20 (2005)
SKKU
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